Background: The increase in frequency and intensity of urban ooding is a global challenge. Flooding directly impacts residents of industrialized cities with aging combined sewer systems, as well as cities with less cen- tralized infrastructure to manage stormwater, fecal sludge, and wastewater. Green infrastructure is growing in popularity as a sustainable strategy to mimic nature-based ood management. Although its technical perfor- mance has been extensively studied, little is known about the e ects of green stormwater infrastructure on human health and social well-being. Methods: We conducted a multidisciplinary systematic review of peer-reviewed and gray literature on the e ects of green infrastructure for stormwater and ood management on individuals’, households’, and communities’ a) physical health; b) mental health; c) economic well-being; and d) ood resilience and social acceptance of green infrastructure. We systematically searched databases such as PubMed, Web of Science, and Scopus; the rst 300 results in Google Scholar; and websites of key organizations including the United States Environmental Protection Agency. Study quality and strength of evidence was assessed for included studies, and descriptive data were extracted for a narrative summary. Results: Out of 21,213 initial results, only 18 studies reported health or social well-being outcomes. Seven of these studies used primary data, and none allowed for causal inference. No studies connected green infra- structure for stormwater and ood management to mental or physical health outcomes. Thirteen studies were identi ed on economic outcomes, largely reporting a positive association between green infrastructure and property values. Five studies assessed changes in perceptions about green infrastructure, but with mixed results. Nearly half of all included studies were from Portland, Oregon. Conclusions: This global systematic review highlights the minimal evidence on human health and social well- being relating to green infrastructure for stormwater and ood management. To enable scale-up of this type of infrastructure to reduce ooding and improve ecological and human well-being, widespread acceptance of green infrastructure will be essential. Policymakers and planners need evidence on the full range of bene ts from di erent contexts to enable nancing and implementation of instfrastructure options, especially in highly ur- banized, ood-prone settings around the world. Therefore, experts in social science, public health, and program evaluation must be integrated into interdisciplinary green infrastructure research to better relate infrastructure design to tangible human outcomes.